Efficient In-Vivo Tumor Targeting of Chitosan-Conjugated, Pluronic-Based Nano-Carriers
نویسندگان
چکیده
Statement of Purpose: Various nanoparticle systems with a long blood circulation time and a high tumor accumulation have been reported for cancer diagnosis and treatment based on their EPR (enhanced permeability and retention) effect [1,2]. Here, we prepared several Pluronic-based nano-carriers attached with an NIR dye, and characterized their cellular uptake and in-vivo tumor targeting efficiency focused on the effect of chitosan and the structure of Pluronic.
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